
The first time characterized by J.L.W. Thudichum (1884), are chemically and structurally, sphingomyelin was included into the phospholipid fatty group, but due to the chemical skeleton named sphingosin then usually inserted as well as sphingolipid. This is because in the sphingomyelin molecule compounds containing phosphate and choline. Currently, choline compounds were already known to be involved in brain development.
In the body, sphingomyelin can dibiosintesis by the body from the amino acid serine with the help of several cofactors such as palmitic acid, vitamin B6, niacin and riboflavin to obtain the basic framework, sphingosin. Addition of one molecule of fatty acid on amine groups of sphingosin will produce adhesion molecules and subsequent ceramid fosfokolin the hydroxyl group at the end will produce sphingomyelin. As with phosphatidylcholine, a type of phospholipid, a sphingomyelin molecule contains one molecule of choline. So besides having a function as penyelimut, sphingomyelin choline also acts as a carrier.
In contrast to AA and DHA, sphingomyelin plays a role in the formation of myelin and myelin itself serves as a "blanket" of nerve cells that help these impulses in nerve cells .. Penyelimutan process of axons (fibers) of nerve cells known as myelinasi.
Myelin is a sheet of lipid-rich who are the main components of sphingomyelin and other sphingolipid metabolites and also serves to speed up the impulses from one nerve cell to nerve cells, muscle or other target cells. This function makes the sphingomyelin start ogled by scientists to examine further how important her role in the development of nerve cells is good and healthy.
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